In The News

CDI Patient Advisory Board member Emmett Smith awarded KidneyX Patient Innovator Prize for a novel dialysis catheter.

March 10, 2020

A Novel Dialysis Catheter to Prevent Vessel Backwall Penetration

The device contained herein provides a solution to the inherent issue of infiltration caused by the current design of dialysis needles. It will also provide better health and quality of life to those affected by Kidney disease and having to use dialysis as a treatment. The device accomplishes this by using a catheter style cannula. This ensures that the needle is retracted from the arm immediately after the initial stick. The catheter is left in the fistula or graft, and dialysis can begin.

CDI Patient Advisory Board member Nichole Jefferson part of Home Dialyzors United team awarded KidneyX Patient Innovator Prize for a real-time home hemodialysis kit

March 10, 2020

Development of a Real-Time Home Hemodialysis Toolkit

Led by home dialyzor Nieltje Gedney, our team is developing a toolkit that gives home dialyzors real-time information and feedback that can be used to improve modality outcomes. The product’s user interface and content will be built using data and feedback collected from dialyzors and other stakeholders such as care partners, family members and clinicians. The toolkit will also interface with a professionally moderated social media support network, giving dialyzors access to tips and advice on-demand, 24/7.

CDI receives KidneyX Phase I Redesign Dialysis Prize in recognition for submissions for a portable/wearable hemodialysis device (the AKTIV) and for a novel vascular graft design.

April 29, 2019

The Ambulatory Kidney to Improve Vitality (AKTIV)

Kidney disease affects over 30 million adults in the US, is the 9th leading cause of death, and remains a devastating medical, social, and economic problem for patients, families, and society worldwide. With the rapid increase of obesity, diabetes, and hypertension, the number of ESRD patients is likely to increase for decades. The only treatments available for ESRD patients are dialysis or kidney transplant. For those on dialysis, deaths occur primarily from complications associated with kidney failure, comorbidities, and dialysis treatment, including cardiovascular disease and infections. Risks of complications from infections, blood clots, and vascular access failure remain exceedingly high. Current dialysis technology requires most patients travel to a dialysis center and spend 4-6 hours tethered to large dialysis machines, 3 times/week for the rest of their lives. Patients are unable to live full and productive lives due to the physical toll dialysis takes and the excessive amount of treatment time required.

Dialysis as a life-sustaining therapy for irreversible kidney failure was pioneered at the University of Washington; over 50 years later, there have been few patient-transformational technical innovations. The UW Center for Dialysis Innovation (CDI) is reinventing dialysis by applying new ideas, 21st century technologies, and exceptional science. We envision hemodialysis therapy that is accessible, complication-free, and more effectively emulates healthy kidney function with dramatically improved outcomes and quality of life for patients.

The CDI will transform dialysis using state-of-the-art biomaterials and engineering technologies. Our high-powered, multidisciplinary team is developing revolutionary dialysis technologies, focused on developing the AKTIV (Ambulatory Kidney to Improve Vitality): a wearable, miniaturized dialysis system that is low-cost, water-efficient, requires minimal anticoagulation, offers complication-free blood access, and is patient-friendly. The AKTIV will provide sustained life, and higher quality, more productive lives for patients worldwide, allowing almost unlimited mobility, dramatically reduce pharmaceutical burden, and reduce dietary restrictions.